SMART O2: Adjusting oxygen to patient needs. An observation study of oxygen administration to critically ill children admitted to Holy Innocents Children’s Hospital in Mbarara, Uganda


Reporting Organization:Institute for Global Health at BC Children’s and Women’s Hospital
Total Budget ($CAD): $ 40,000
Timeframe:January 25, 2024 - May 21, 2025
Status:Fermé
Contact Information: Charly Huxford
[email protected]

Partner & Funder Profiles


Reporting Organization


Institute for Global Health at BC Children’s and Women’s Hospital

Participating Organizations


Funders (Total Budget Contribution)


  • NGOs

    • BC Children's Hospital Foundation (100%)
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Location


Country - Total Budget Allocation


Uganda - $ 40,000.00 (100.00%)

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Areas of Focus


Health - Total Budget Allocation


Health Systems, Training & Infrastructure (0 %)

Primary Health Care (0 %)

Newborn & Child Health (0 %)

Adolescent Health (0 %)

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Description


In low- and middle-income countries (LMICs), the scarcity of medical oxygen contributes to preventable child deaths—particularly from hypoxemic pneumonia and sepsis. Even when oxygen is available, inefficient use can lead to waste, shortages, and delays in care for critically ill patients. Oxygen is recognized by the World Health Organization (WHO) as an essential medicine, yet millions of children who need it never receive it. UNICEF estimates that severe pneumonia alone causes critical hypoxemia in over 4 million children under five in LMICs each year, and access to oxygen therapy can reduce in-hospital mortality by up to 35%.

A key challenge is ensuring that oxygen is used appropriately. While supplemental oxygen is life-saving, excessive or unnecessary administration can cause harm, such as oxygen toxicity or blindness in infants, and depletes already limited supplies. WHO guidelines recommend using pulse oximetry—a quick, non-invasive measure of oxygen saturation (SpO₂)—to monitor children receiving oxygen therapy at least twice a day. However, there are currently no widely available tools to help health workers adjust oxygen flow rates in real time based on continuous SpO₂ measurements.

The Smart O₂ project aims to close this gap. Our goal is to develop and validate a clinical algorithm that guides regular oxygen titration for critically ill children using continuous SpO₂ monitoring. By matching oxygen supply to actual patient needs, Smart O2 aims to:

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Target Population


Gender and age: Adolescent females Adolescent males Under-5 children Children, girls Children, boys
Descriptors: Rural Urban
Total Direct Population:96
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Outputs


3Training
5Research
1Clinical tool
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Results & Indicators


Expected Results


Achieved Results


A total of 96 children were enrolled, with comprehensive data collected on oxygen use, pulse oximetry measurements, and vital signs. Over 50 healthcare workers received training on the principles of oxygen titration, enhancing their capacity to deliver safe and efficient oxygen therapy.

Indicators


None Selected
  • None Selected
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    Associated Projects (If applicable)


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